New Release Books by Matthew Cobb

The thrilling and terrifying history of genetic engineering In 2018, scientists manipulated the DNA of human babies for the first time. As biologist and historian Matthew Cobb shows in As Gods, this achievement was one many scientists have feared from the start of the genetic age. Four times in the last fifty years, geneticists, frightened by their own technology, have called a temporary halt to their experiments. They ought to be frightened: Now we have powers that can target the extinction of pests, change our own genes, or create dangerous new versions of diseases in an attempt to prevent future pandemics. Both awe-inspiring and chilling, As Gods traces the history of genetic engineering, showing that this revolutionary technology is far too important to be left to the scientists. They have the power to change life itself, but should we trust them to keep their ingenuity from producing a hellish reality?

''Brilliant .. I cannot recommend this book strongly enough'' - Henry Marsh, New Statesman (about The Idea of the Brain) A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.

Our sense of smell - or olfaction as it is technically known - is our most enigmatic sense. It can conjure up memories, taking us back to very specific places and emotions, whilst powerful smells can induce strong feelings of hunger or nausea. In the animal kingdom smell can be used to find food, a mate, or a home; to sense danger; and to send and receive complex messages with other members of a species. Yet despite its fundamental importance in our mental life and in the existence of all animals, our scientific understanding of how smell works is limited. In this Very Short Introduction, Matthew Cobb describes the latest scientific research on smell in humans and other mammals, in insects, and even in fish. He looks at how smell evolved, how animals use it to navigate and communicate, and disorders of smell in humans. Understanding smell, especially its neurobiology, has proved a big challenge, but olfactory science has revealed genetic factors that determine what we can and cannot smell, and why some people like a given smell while others find it unbearable. He ends by considering future treatments for smell disorders, and speculating on the role of smell in a world of robots. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

An "elegant", "engrossing" (Carol Tavris, Wall Street Journal) examination of what we think we know about the brain and why -- despite technological advances -- the workings of our most essential organ remain a mystery. "I cannot recommend this book strongly enough."--Henry Marsh, author of Do No Harm For thousands of years, thinkers and scientists have tried to understand what the brain does. Yet, despite the astonishing discoveries of science, we still have only the vaguest idea of how the brain works. In The Idea of the Brain, scientist and historian Matthew Cobb traces how our conception of the brain has evolved over the centuries. Although it might seem to be a story of ever-increasing knowledge of biology, Cobb shows how our ideas about the brain have been shaped by each era''s most significant technologies. Today we might think the brain is like a supercomputer. In the past, it has been compared to a telegraph, a telephone exchange, or some kind of hydraulic system. What will we think the brain is like tomorrow, when new technology arises? The result is an essential read for anyone interested in the complex processes that drive science and the forces that have shaped our marvelous brains.

''Brilliant .. I cannot recommend this book strongly enough'' - Henry Marsh, New Statesman (about The Idea of the Brain)A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction.But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.

Everyone has heard of the story of DNA as the story of Watson and Crick and Rosalind Franklin, but knowing the structure of DNA was only a part of a greater struggle to understand life’s secrets. Life’s Greatest Secret is the story of the discovery and cracking of the genetic code, the thing that ultimately enables a spiraling molecule to give rise to the life that exists all around us. This great scientific breakthrough has had farreaching consequences for how we understand ourselves and our place in the natural world, and for how we might take control of our (and life’s) future. Life’s Greatest Secret mixes remarkable insights, theoretical dead-ends, and ingenious experiments with the swift pace of a thriller. From New York to Paris, Cambridge, Massachusetts, to Cambridge, England, and London to Moscow, the greatest discovery of twentieth-century biology was truly a global feat. Biologist and historian of science Matthew Cobb gives the full and rich account of the cooperation and competition between the eccentric characters—mathematicians, physicists, information theorists, and biologists—who contributed to this revolutionary new science. And, while every new discovery was a leap forward for science, Cobb shows how every new answer inevitably led to new questions that were at least as difficult to answer: just ask anyone who had hoped that the successful completion of the Human Genome Project was going to truly yield the book of life, or that a better understanding of epigenetics or “junk DNA” was going to be the final piece of the puzzle. But the setbacks and unexpected discoveries are what make the science exciting, and it is Matthew Cobb’s telling that makes them worth reading. This is a riveting story of humans exploring what it is that makes us human and how the world works, and it is essential reading for anyone who’d like to explore those questions for themselves.

''I had thought that for me there could never again be any elation in war. But I had reckoned without the liberation of Paris - I had reckoned without remembering that I might be a part of that richly historic day. We were in Paris on the first day - one of the great days of all time.'' (Ernie Pyle, US war correspondent) The liberation of Paris was a momentous point in twentieth-century history, yet it is now largely forgotten outside France. Eleven Days in Augustis a pulsating hour-by-hour reconstruction of these tumultuous events that shaped the final phase of the war and the future of France, told with the pace of a thriller. While examining the conflicting national and international interests that played out in the bloody street fighting, it tells of how, in eleven dramatic days, people lived, fought and died in the most beautiful city in the world. Based largely on unpublished archive material, including secret conversations, coded messages, diaries and eyewitness accounts, Eleven Days in Augustshows how these August days were experienced in very different ways by ordinary Parisians, Resistance fighters, French collaborators, rank-and-file German soldiers, Allied and French spies, the Allied and German High Commands. Above all, it shows that while the liberation of Paris may be attributed to the audacity of the Resistance, the weakness of the Germans and the strength of the Allies, the key to it all was the Parisians who by turn built street barricades and sunbathed on the banks of the Seine, who fought the Germans and simply tried to survive until the Germans finally surrendered, in a billiard room at the Prefecture of Police. One of the most iconic moments in the history of the twentieth century had come to a close, and the face of Paris would never be the same again.

The French resistance to Nazi occupation during World War II was a struggle in which ordinary people fought for their liberty, despite terrible odds and horrifying repression. Hundreds of thousands of Frenchmen and women carried out an armed struggle against the Nazis, producing underground anti-fascist publications and supplying the Allies with vital intelligence. Based on hundreds of French eye-witness accounts and including recently-released archival material, The Resistanceuses dramatic personal stories to take the reader on one of the great adventures of the 20thcentury. The tale begins with the catastrophic Fall of France in 1940, and shatters the myth of a unified Resistance created by General de Gaulle. In fact, De Gaulle never understood the Resistance, and sought to use, dominate and channel it to his own ends. Brave men and women set up organisations, only to be betrayed or hunted down by the Nazis, and to die in front of the firing squad or in the concentration camps. Over time, the true story of the Resistance got blurred and distorted, its heroes and conflicts were forgotten as the movement became a myth. By turns exciting, tragic and insightful, The Resistancereveals how one of the most powerful modern myths came to be forged and provides a gripping account of one of the most striking events in the 20thcentury.

Madelyn Drielle is an oneiromancer. That is, someone who can see the future in her dreams. For most of her life, she didn''t think there were others like her out there. When she finds out there are, she''ll learn they can be a little... aggressive. Join or heroine in, "The Bridge," "The Summoned," and "The Eyes" as she meets new oneiromancers and deals with their unique abilities.

Generation is the story of the exciting, largely forgotten decade during the seventeenth century when a group of young scientists-Jan Swammerdam, the son of a Protestant apothecary, Nils Stensen (also known as Steno), a Danish anatomist who first discovered the human tear duct, Reinier de Graaf, the attractive and brilliant son of a rich and successful Catholic architect, and Antoni Leeuwenhoek, a self-taught draper-dared to challenge thousands of years of orthodox thinking about where life comes from. By meticulous experimentation, dissection, and observation with the newly invented microscope, they showed that like breeds like, that all animals come from an egg, that there is no such thing as spontaneous generation, and that there are millions of tiny, wriggling "eels" in semen. However, their ultimate inability to fully understand the evidence that was in front of them led to a fatal mistake. As a result, the final leap in describing the process of reproduction-which would ultimately give birth to the science of genetics-took nearly two centuries for humanity to achieve. Including previously untranslated documents, Generation interweaves the personal stories of these scientists against a backdrop of the Dutch "Golden Age." It is a riveting account of the audacious men who swept away old certainties and provided the foundation for much of our current understanding of the living world.

Where do we come from? Where do animals come from? For thousands of years we really had no clue how living things were created -- great thinkers like Aristotle and Plato had attempted to explain what became known as the problem of ''generation'', but neither really had the tools or the insight to solve the mystery. The result was a wealth of weird and wonderful ideas about the components necessary to create new life -- blood, ''vapours'', strange pulses in the air. Nor did people make intuitive leaps that now seem self-evident: it was widely accepted that animals could breed different species, for example; the notion that two sheep can only make another sheep is a surprisingly modern idea.But all this confusion changed in a flurry of discovery in the mid-seventeenth century. In just a decade, a group of young scientists in Europe, all known to each other and in competition with each other, established the existence first of the human egg and then of the human sperm. At last, the building blocks were in place -- although, in one of the great ironies of science, it would be another 150 years before someone worked out how fertilisation actually took place.Focusing on the personalities and rivalries of this extraordinary period, Matthew Cobb has shed new light not just on an under-reported story of science but on our very nature -- what makes us, and how little we still know about one of the greatest miracles of Nature.

Where do we come from? For thousands of years we really had no clue how living things were created -- great thinkers like Aristotle and Plato had attempted to explain what became known as the problem of ''generation'', but neither really had the tools or the insight to solve the mystery. The result was a wealth of weird and wonderful ideas about the components necessary to create new life -- blood, ''vapours'', strange pulses in the air. It was also widely accepted that animals could breed different species; the notion that two sheep can only make another sheep is a surprisingly modern idea. But all this confusion changed in a flurry of discovery in the mid-seventeenth century. In just a decade, a group of young scientists in Europe established the existence first of the human egg and then of the human sperm. At last, the building blocks were in place -- although, in one of the great ironies of science, it would be another 150 years before someone worked out how fertilisation actually took place. Focusing on the personalities and rivalries of this extraordinary period, Matthew Cobb has shed new light not just on an under-reported story of science but on our very nature -- and how little we still know about one of the greatest miracles of Nature.