New Releases by Ellen Hopkins

Polluted air commonly contains suspended particulate matter (PM), including large numbers of particles in the ultrafine or nano size fraction. Epidemiological and toxicological research indicates an association between the particulate component of air pollution and adverse respiratory and cardiovascular health effects in humans. The relationship between airborne particles and the observed health effects is not yet well understood mechanistically, although particle size and chemical composition appear to be critical factors conferring potential toxicity. We hypothesized that inhaled particulate of sufficiently small size could contribute to the observed health effects by entering the brain via olfactory nerve tracts and provoking a pro-inflammatory response in targeted tissues. To investigate the hypothesis, we undertook a series of experiments in which mice were briefly exposed to nanoparticle aerosols. In separate experiments, mice were exposed to aerosols of ultrafine iron oxide (Fe2O3) or CdSe-ZnS nanocrystals (quantum dots). Following exposure, respiratory tract and central nervous system tissues were examined for the presence of these particles and exposure-related biological responses. Olfactory-derived primary cell cultures also were exposed to quantum dots. Particles were detected using a combination of techniques including standard and fluorescent light microscopy, electron microscopy, and elemental analysis. Responses were measured using histochemical and biochemical methods.In mice exposed to ultrafine iron oxide aerosols, we found evidence of particle uptake and pro-inflammatory responses in the lung and the olfactory bulb. In mice exposed to quantum dot aerosols, we found evidence of particle uptake and pro-inflammatory responses in the olfactory bulb. Uptake was more pronounced for quantum dots than iron, with quantum dots detected in olfactory bulbs less than three hours post-exposure. Electron microscopy revealed quantum dots within axons of the olfactory nerve tracts connecting the nasal mucosa to the olfactory bulbs. Following in vitro exposure, we found evidence of selective uptake of quantum dots by distinct subpopulations of cells. In mixed glia-neuron cultures, particle uptake was most prominent in microglia, while in olfactory epithelial cultures particle uptake was essentially limited to unidentified cells morphologically similar to olfactory stem cells. Our results clearly demonstrate that inhaled particles can enter the brain via olfactory nerves.

From the New York Times bestselling author of the sizzling romantic suspense Love Lies Beneath, three female friends face midlife crises in a no-holds-barred exploration of sex, marriage, and the fragility of life. Holly, filled with regret for being a stay-at-home mom, sheds sixty pounds and loses herself in the world of extramarital sex. But will it truly bring the fulfillment she is searching for? Andrea, a single mom and avowed celibate, watches her friend Holly’s meltdown with a mixture of concern and contempt. Holly is throwing away what Andrea has spent her whole life searching for—a committed relationship with a decent guy. So would it be such a bad thing if Andrea picks up Holly’s castaway husband? Marissa has more than her fair share of challenges—a rebellious teenage son, a terminally ill daughter, and a husband who buries himself in his work rather than face the facts. As one woman’s marriage unravels, another’s rekindles. As one woman’s family comes apart at the seams, another’s reconfigures into something bigger and better. In this story of connections and disconnections, one woman’s up is another one’s down, and all of them will learn the meaning of friendship, betrayal, and forgiveness. Unflinchingly honest, emotionally powerful, surprisingly erotic, Triangles is the ultimate page-turner. Hopkins’s gorgeous, expertly honed poetic verse perfectly captures the inner lives of her characters: Sometimes it happens like that. Sometimes you just get lost. Get lost in the world of Triangles, where the lives of three unforgettable women intersect, and where there are no easy answers.

Collection includes two annotated galley proofs of Ellen Hopkins'' young adult novel, Tilt. The first galley proof bears editorial annotations and is signed by the author and dedicated to the Ted Hipple Collection. The second typescript bears editorial annotations and is accompanied by editorial requests to the copyeditor and an InDesign memo relating to the book layout.

Collection includes two annotated galley proofs of Ellen Hopkins'' young adult novel, Smoke. The first galley proof is signed and dedicated to the Ted Hipple Collection and contains limited editorial annotations. The second galley proof bears more extensive editorial annotations. Also included is publisher correspondence and an InDesign memo relating to book layout.

Collection includes two galley proofs of Ellen Hopkins'' young adult novel, Fallout. The typescript conains editorial notes and a list of line item edits. Both galley proofs bear extensive editorial annotations, and the first is signed by the author and dedicated to the Ted Hipple Collection. Also included is a design memo for the book.

Fans of the literary phenomenon known as the Twilight series can''t help wanting more. A New Dawn gives it to them, inviting readers to join some of their favorite YA authors as they look at the series with fresh eyes and fall in love with Edward, Bella, and the rest of Forks, Wash., all over again. Edited by bestselling author Ellen Hopkins, A New Dawn is packed with the same debates readers engage in with friends: Should Bella have chosen Edward or Jacob? How much control do Meyer''s vampires and werewolves really have over their own lives? The collection also goes further: Is Edward a romantic or a (really hot) sociopath? How do the Quileute werewolves compare to other Native American wolf myths? What does the Twilight series have in common with Shakespeare? With contributions from Megan McCafferty, Cassandra Clare, Rachel Caine, and many more, A New Dawn answers these questions and more for a teen (and adult!) audience hungry for clever, view-changing commentary on their favorite series.

Five troubled teenagers fall into prostitution as they search for freedom, safety, community, family, and love in this #1 New York Times bestselling novel from Ellen Hopkins. “When all choice is taken from you, life becomes a game of survival.” Five teenagers from different parts of the country. Three girls. Two guys. Four straight. One gay. Some rich. Some poor. Some from great families. Some with no one at all. All living their lives as best they can, but all searching…for freedom, safety, community, family, love. What they don’t expect, though, is all that can happen when those powerful little words “I love you” are said for all the wrong reasons. Five moving stories remain separate at first, then interweave to tell a larger, powerful story—a story about making choices, taking leaps of faith, falling down, and growing up. A story about kids figuring out what sex and love are all about, at all costs, while asking themselves, “Can I ever feel okay about myself?” A brilliant achievement from New York Times bestselling author Ellen Hopkins—who has been called “the bestselling living poet in the country” by Mediabistro.com—Tricks is a book that turns you on and repels you at the same time. Just like so much of life.

Where is the line between truth and fiction? Why do love and addiction so often go hand in hand? What does the real "Kristina" think about the way her story is told in Crank and Glass? Crank and Glass have always been more than just stories. Join their author Ellen Hopkins and a host of other writers as they delve deep into Kristina''s story, from the straight truth on the physical effects of methamphetamine addiction to the psychological consequences of keeping secrets (and how Hopkins'' books have encouraged so many teens to reveal theirs). With an essay by Ellen''s real-life daughter (the basis for the character of "Kristina") that tells her version of the events that inspired the books—along with perspectives from "Scott," "Jake," and 10-year-old "Hunter," the baby from Crank—Flirtin'' with the Monster is a compelling journey through the complexities of Hopkins'' beloved bestselling works.

Collection includes one galley proof of Ellen Hopkins'' young adult novel, Tricks. The galley proof bears extensive editorial annotations by P.G. Signed by the author and dedicated to the Ted Hipple Collection.

Beneath their perfect family façade, twin sisters struggle alone with impossible circumstances and their own demons until they finally learn to fight for each other in this poignant tour de force from #1 New York Times bestselling author Ellen Hopkins. Sixteen-year-old Kaeleigh and Raeanne are identical down to the dimple. As daughters of a district court judge father and a politician mother, they are an all-American family…on the surface. Underneath run very deep and damaging secrets. What really happened in the car accident that Daddy caused? And why is Mom never home, always running far away to pursue some new dream? The girls themselves have become hopelessly divided over the years. Sick of losing Daddy’s game of favorites, Raeanne turns to painkillers, alcohol, and sex to dull her pain her anger. Kaeleigh tries to be her father’s perfect little flower, but being the misplaced focus of his sexual attention has her seeking control anywhere she can—even if it means cutting herself and unhealthy binge and purge eating. Secrets like the ones the twins are harboring are not meant to be kept—from each other or anyone else. Before long, it''s obvious that neither sister can handle their problems alone, and one must step up to save the other, but the question is…who?

Provides an overview of the United States Special Forces, including their history, weapons, and vehicles.

From the bestselling author of Crank, the story of three kids whose lives collide at a mental hospital after each attempts suicide. Sometimes you don''t wake up. But if you happen to, you know things will never be the same. Three lives, three different paths to the same destination: Aspen Springs, a psychiatric hospital for those who have attempted the ultimate act—suicide. Vanessa is beautiful and smart, but her secrets keep her answering the call of the blade. Tony, after suffering a painful childhood, can only find peace through pills. And Conner, outwardly, has the perfect life. But dig a little deeper and find a boy who is in constant battle with his parents, his life, himself. In one instant each of these young people decided enough was enough. They grabbed the blade, the bottle, the gun—and tried to end it all. Now they have a second chance, and just maybe, with each other''s help, they can find their way to a better life—but only if they''re strong and can fight the demons that brought them here in the first place.

Niki Burnham, Terri Clark, Ellen Hopkins, and Lynda Sandoval give us four tales about the end of first love.How does anyone survive? Read on and find out.Each story showcases the writer''s signature style: Niki Burnham keeps it smart and sassy; Terri Clark brings a touch of fantasy; Ellen Hopkins tells her story in verse; and no one does funny like Lynda Sandoval.For teens looking for something to get them through the pain, this is just the prescription!

Describes the equipment, skills, conservation issues, and safety concerns of freshwater fishing.

A New Look at a Beloved Block Book! Give your quilts an "art-school graduate look" using simple and fast methods. Mary Ellen breaks down complex piecing into simple units. Tons of tips cover fabrics, supplies, cutting, pressing, piecing and more. Learn to make perfect pieced triangles the hassle-free way. Lots of setting options for all your blocks. If you''ve ever looked at a complex pieced block and wondered if you could make it, this is the book for you. Mary Ellen deconstructs all kinds of blocks into easy-to-piece units: from Rail Fence to 18-Patch blocks, all you''ll need is squares and triangles! First issued over fifteen years ago, this volume has been updated extensively.

Come explore the Great Outdoors. Outdoor enthusiasts will learn about the equipment they need, the techniques to employ, and the conservation measures that will ensure a great adventure.

Provides an overview of the types of vehicles used by the United States Air Force and their purposes.

Describes the life cycle, characteristics, and varieties of stars, including novas, variables, and neutron stars.

This book explains that with every question that is answered about the universe, a dozen more are raised and discusses some of the cosmic puzzles that have been solved.

Describes the lives and careers of the sisters Katherine and Marjorie Stinson, pioneers who battled gender discrimination in order to be air pilots.

Army! Navy! Air Force! Special Forces! This detail-rich focuses on the military branches and their fighting vehicles. Through action photos and a guidebook design, readers will learn the history and function of each branch, who works there, and what it''s like to live on a military base.

Provides an overview of the United States Air Force, including its history, weapons, and vehicles.

Provides an overview of the United States Special Forces, including their history, weapons, and vehicles.

This 48-page, general information book for children, 8-12, is beautifully illustrated with full-color photographs, graphics, maps and charts. Discover Nevada''s cities, deographics and industries, geography, geology and hydrology, government, prehistory and history, early exploration and settlement, native Nevadans, great women, mining, ranching and railroads, environmental issues, and flora and fauna.

Describes the equipment, skills, conservation issues, and safety concerns of fly fishing.

Take a journey to the Amazon rain forest, and learn about the plants and animals that live there and what is being done to save this natural resource.

Describes the U.S. Army Golden Knights, their history, aircraft, maneuvers, and team members.

Describes the U.S. Air Force Thunderbirds, their history, mission, aircraft, maneuvers, and team members.