Best Selling Books by Scott Williams

Written by a local author, this guide includes details about hotels, restaurants, annual events, attractions, nightlife, parks and recreation, real estate, and much more.

Ralph Richards is a disillusioned bachelor who falls in love with almost every woman he sees. With his inability to hold down a job and his overwhelming capacity for anger and depression, his world is a swampland of emotional turmoil, and things are only getting worse. Lunatic is Ralph's story, but there are also 5 others here, including Destitution, a tale of two aging degenerate street bums, and Psycho Joe, which recounts the early exploits of a 12 year-old serial killer.

The results of this thesis highlight the significance of implementing lean manufacturing, especially in a dynamic environment. As the instability in the environment increases, profitability decreases. Therefore, an increase in leanness by boosting inventory turns can compensate for the volatility and create enhanced productivity measures and financial results.

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The current project sought to identify changes in olfactory-related behavior in hamsters infected with the HY transmissible mink encephalopathy (HY TME) strain of the pathological form of the prion protein. Experiment 1 was conducted to validate an olfactory preference paradigm for use with Syrian golden hamsters. An experimental group was induced with anosmia by treating them with methimazole. In an olfactory preference test in which the time subjects spent investigating attractive, aversive, and neutral olfactory stimuli were assessed, control animals spent a significantly longer amount of time investigating the attractive versus aversive scents. The methimazole-treated group did not demonstrate this pattern. Experiment 2 investigated changes in olfactory behavior as a result of prion infection. A group of hamsters was infected with HY TME and subjected to olfactory preference testing at four time points: 20, 40, 60, and 80 days post inoculation. In addition, parallel subjects were sacrificed and submitted to immunohistochemical analysis in order to examine the proliferation of HY TME throughout olfactory-related brain structures with the intention of relating behavioral changes to the progression of prion infection. Results indicated that HY TME subjects lost their ability to perceive the attractive scent early in the disease. However, avoidance of the aversive scent was retained until much later. The immunohistochemistry revealed an initial appearance of the pathologic prion at 20 days post inoculation in the glomeruli of the olfactory bulb. Widespread infection throughout all olfactory structures was observed at 40 days post inoculation and beyond. These results suggested a differential sensory loss to the olfactory stimuli that may have been due to initial infection in the glomeruli and later infection in other olfactory structures. These findings support the utility of discrimination paradigms for the diagnosis of prion diseases.

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"The transparent story of a remarkable life's journey--to the highest level of success as a basketball player, the NBA. The depths of personal trauma and pain are core moments in this journey Scott Williams takes us on."--Publisher's description.