Most Popular Books by James D. Watson

Fifty years ago, James D. Watson, then just twentyfour, helped launch the greatest ongoing scientific quest of our time. Now, with unique authority and sweeping vision, he gives us the first full account of the genetic revolution—from Mendel’s garden to the double helix to the sequencing of the human genome and beyond. Watson’s lively, panoramic narrative begins with the fanciful speculations of the ancients as to why “like begets like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel first deduced the basic laws of inheritance. But genetics as we recognize it today—with its capacity, both thrilling and sobering, to manipulate the very essence of living things—came into being only with the rise of molecular investigations culminating in the breakthrough discovery of the structure of DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s graceful curves was the key to a whole new science. Having shown that the secret of life is chemical, modern genetics has set mankind off on a journey unimaginable just a few decades ago. Watson provides the general reader with clear explanations of molecular processes and emerging technologies. He shows us how DNA continues to alter our understanding of human origins, and of our identities as groups and as individuals. And with the insight of one who has remained close to every advance in research since the double helix, he reveals how genetics has unleashed a wealth of possibilities to alter the human condition—from genetically modified foods to genetically modified babies—and transformed itself from a domain of pure research into one of big business as well. It is a sometimes topsy-turvy world full of great minds and great egos, driven by ambitions to improve the human condition as well as to improve investment portfolios, a world vividly captured in these pages. Facing a future of choices and social and ethical implications of which we dare not remain uninformed, we could have no better guide than James Watson, who leads us with the same bravura storytelling that made The Double Helix one of the most successful books on science ever published. Infused with a scientist’s awe at nature’s marvels and a humanist’s profound sympathies, DNA is destined to become the classic telling of the defining scientific saga of our age.

James D. Watson looks back on his extraordinary and varied career - from its beginnings as a schoolboy in Chicago''s South Side to the day he left Harvard almost 50 years later, world-renowned as the co-discoverer of DNA - and considersthe lessons he has learnt along the way. The result is both anengagingly eccentric memoir and an insightful compendiumof lessons in life for aspiring scientists. Avoid Boring People, is a quirky, original, wise, and infuriatingly un-put-downable blend of candid anecdotes and revealing insights into the life of one of the greatest scientists of the 20th century.

Portions of this book were first published in The Atlantic monthly.

By identifying the structure of DNA, Francis Crick and James Watson revolutionized biochemistry and won a Nobel Prize. All the time Watson was only twenty-four, a young zoologist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of sciences'' greatest unsolved mysteries gives a dazzlingly clear picture of a world of scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick''s desperate efforts to beat Linus Pauling to the identification of the basic building block of life.

In 1953, two young and unknown scientists, James Watson and Francis Crick, sparked a worldwide revolution with their discovery of the molecular composition of DNA. In this collection of outspoken and topical essays, speeches and reports, Watson offers his unique insight into the advance of molecular genetics, the prospect of curing cancer over the next decade, how human genetic knowledge is likely to be used, particularly in relation to cloning and genetically modified food, as well as shedding light on his early life and career.

In 1953 Watson and Crick discovered the double helical structure of DNA and Watson''s personal account of the discovery, The Double Helix, was published in 1968. Genes, Girls and Gamow is also autobiographical, covering the period from when The Double Helix ends, in 1953, to a few years later, and ending with a Postscript bringing the story up to date. Here is Watson adjusting to new-found fame, carrying out tantalizing experiments on the role of RNA in biology, and falling in love. The book is enlivened with copies of handwritten letters from the larger than life character George Gamow, who had made significant contributions to physics but became intrigued by genes, RNA and the elusive genetic code. This is a tale of heartbreak, scientific excitement and ambition, laced with travelogue and ''50s atmosphere.

On the fiftieth anniversary of Watson and Crick receiving the Nobel Prize, a freshly annotated and illustrated edition of The Double Helix provides new insights into a scientific revolution. Published to mark the fiftieth anniversary of the Nobel Prize for Watson and Crick’s discovery of the structure of DNA, an annotated and illustrated edition of this classic book gives new insights into the personal relationships between James Watson, Frances Crick, Maurice Wilkins, and Rosalind Franklin, and the making of a scientific revolution.

Recombinant DNA, Third Edition, is an essential text for undergraduate, graduate, and professional courses in Genomics, Cell and Molecular Biology, Recombinant DNA, Genetic Engineering, Human Genetics, Biotechnology, and Bioinformatics. The Third Edition of this landmark text offers an authoritative, accessible, and engaging introduction to modern, genome-centered biology from its foremost practitioners. The new edition explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the most relevant and exciting examples of current research and landmark experiments that redefined our understanding of DNA. As a result, students learn how working scientists make real high-impact discoveries. The first chapters provide an introduction to the fundamental concepts of genetics and genomics, an inside look at the Human Genome Project, bioinformatic and experimental techniques for large-scale genomic studies, and a survey of epigenetics and RNA interference. The final chapters cover the quest to identify disease-causing genes, the genetic basis of cancer, and DNA fingerprinting and forensics. In these chapters the authors provide examples of practical applications in human medicine, and discuss the future of human genetics and genomics projects.

In the years following his and Francis Crick’s towering discovery of DNA, James Watson was obsessed with finding two things: RNA and a wife. Genes, Girls, and Gamow is the marvelous chronicle of those pursuits. Watson effortlessly glides between his heartbreaking and sometimes hilarious debacles in the field of love and his heady inquiries in the field of science. He also reflects with touching candor on some of science’s other titans, from fellow Nobelists Linus Pauling and the incorrigible Richard Feynman to Russian physicist George Gamow, who loved whiskey, limericks, and card tricks as much as he did molecules and genes. What emerges is a refreshingly human portrait of a group of geniuses and a candid, often surprising account of how science is done.